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Outline

Our goal is to develop original RIKEN data processing technology and multidimensional measurement technology in order to contribute to understanding biological phenomena. We are especially contributing to the fields of mathematical biology, bio-medical simulations as well as medical diagnostic and treatment technology by researching and developing new data and image processing technologies and establishing new tools for quantification of biological phenomena, intended for researchers both inside and outside RIKEN.

Fields

Engineering, Informatics, Computer Science

Keywords

Multi dimensional image processing, Multi dimensional imaging, Bioengineering, Image analysis, Medical engineering

Subjects

1. Development of algorithms for image processing
2. Development of image processing systems
3. Construction of instrumentation system for bio-research data creation

Selected Publications

1. Yoshizawa, S., Michikawa, T., and Yokota, H., “Topological Delaunay Graph for Efficient 3D Binary Image Analysis”, Int. J. Autom. Technol. 18 (5), 632-650 (2024).
2. Fukatsu, M., Yoshizawa, S., Takemura, H., and Yokota, H., “Bilateral Half-box Image Filtering”, Int. J. Autom. Technol. 18(3), 427-432 (2024).
3. Chu, S., Abe, K., Yokota, H., Cho, D., Hayashi, Y., and Tsai, M.-D., “Deep learning for quantifying spatial patterning and formation process of early differentiated human-induced pluripotent stem cells with micropattern images”, J. Microsc. 296(1), 79-93 (2024).
4. Uematsu, T., Tsuboi, T., Hiraga, K., Tamakoshi, D., Fukushima, T., Sato, M., Nishida, K., Yokota, H., and Katsuno, M.: “Differential impact of fixation characteristics on 3D perception via texture gradient recognition in Parkinson's disease”, Parkinsonism Relat. Disord. 128, (2024).
5. Sakamaki, K., Sakamoto, N., Tsujimura, Y., Iwasaki, T., Kawamura, T., and Nakabayashi, J., “Caspase-mediated cleavage of a scaffold protein, MPRIP, yields a truncated form that is involved in repetitive bleb formation”, FEBS J. 292(9), 2287-2305 (2025).

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